Anti-IL23A antibody

Anti-IL23A antibody

Cat. No.     JC263811
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-IL23A rabbit polyclonal antibody
Applications        ELISA, WB, IHC 
Immunogen               Synthetic peptide of human IL23A
Reactivity                 Human
Content                     0.9 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 IL23A
Full name                 interleukin 23 subunit alpha
Synonyms    P19; SGRF; IL-23; IL-23A; IL23P19
Swissprot    Q9NPF7

Target Background
This gene encodes a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit, IL23R. Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG). In contrast to IL12, which acts mainly on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells.

Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 25-100    
            
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using ml263811(IL23A Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)    
Western blotting
Predicted band size:21 kDa
Positive control:Jurkat cell lysate 
Recommended dilution: 200-1000