- 询价
- gelatins
- JC263726
- 上海
- 2025年07月14日
- Rabbit
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- 详细信息
- 文献和实验
- 技术资料
- 供应商：
江西江蓝纯生物试剂有限公司
- 库存：
大量
- 克隆性：
多克隆
- 保质期：
1年
- 抗体英文名：
Anti-POLG antibody
- 宿主：
Rabbit
- 浓度：
0.6 mg/ml
- 保存条件：
-20°C
- 规格：
25 μl/100 μl/200 μl
Cat. No. JC263726
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-POLG rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human POLG
Reactivity Human, Mouse, Rat
Content 0.6 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol POLG
Full name DNA polymerase gamma, catalytic subunit
Synonyms PEO; MDP1; SCAE; MIRAS; POLG1; POLGA; SANDO; MTDPS4A; MTDPS4B
Swissprot P54098
Target Background
Mitochondrial DNA polymerase is heterotrimeric, consisting of a homodimer of accessory subunits plus a catalytic subunit. The protein encoded by this gene is the catalytic subunit of mitochondrial DNA polymerase. The encoded protein contains a polyglutamine tract near its N-terminus that may be polymorphic. Defects in this gene are a cause of progressive external ophthalmoplegia with mitochondrial DNA deletions 1 (PEOA1), sensory ataxic neuropathy dysarthria and ophthalmoparesis (SANDO), Alpers-Huttenlocher syndrome (AHS), and mitochondrial neurogastrointestinal encephalopathy syndrome (MNGIE). Two transcript variants encoding the same protein have been found for this gene.
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm and Cell membrane
Positive control: Human liver cancer
Recommended dilution: 20-100 Predicted cell location: Cytoplasm and Cell membrane
Positive control: Human brain
Recommended dilution: 20-100
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using ml263726(POLG Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using ml263726(POLG Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
ELISA
Recommended dilution: 5000-10000
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