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- 详细信息
- 技术资料
- 供应商:
江西江蓝纯生物试剂有限公司
- 库存:
大量
- 克隆性:
多克隆
- 保质期:
1年
- 抗体英文名:
Anti-CACNA2D2 antibody
- 宿主:
Rabbit
- 浓度:
0.5 mg/ml
- 保存条件:
-20°C
- 规格:
25 μl/100 μl/200 μl
Anti-CACNA2D2 antibody
Cat. No. JC263357
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-CACNA2D2 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human CACNA2D2
Reactivity Human, Mouse, Rat
Content 0.5 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol CACNA2D2
Full name calcium voltage-gated channel auxiliary subunit alpha2delta 2
Synonyms CACNA2D
Swissprot Q9NY47
Target Background
Calcium channels mediate the entry of calcium ions into the cell upon membrane polarization. This gene encodes the alpha-2/delta subunit of the voltage-dependent calcium channel complex. The complex consists of the main channel-forming subunit alpha-1, and auxiliary subunits alpha-2/delta, beta, and gamma. The auxiliary subunits function in the assembly and membrane localization of the complex, and modulate calcium currents and channel activation/inactivation kinetics. The subunit encoded by this gene undergoes post-translational cleavage to yield the extracellular alpha2 peptide and a membrane-anchored delta polypeptide. This subunit is a receptor for the antiepileptic drug, gabapentin. Mutations in this gene are associated with early infantile epileptic encephalopathy. Single nucleotide polymorphisms in this gene are correlated with increased sensitivity to opioid drugs. Alternative splicing results in multiple transcript variants encoding different isoforms.
Applications
Immunohistochemistry
Predicted cell location: Cell membrane
Positive control: Human colorectal cancer
Recommended dilution: 25-100
The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using ml263357(CACNA2D2 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)
ELISA
Recommended dilution: 5000-10000
Cat. No. JC263357
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-CACNA2D2 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human CACNA2D2
Reactivity Human, Mouse, Rat
Content 0.5 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol CACNA2D2
Full name calcium voltage-gated channel auxiliary subunit alpha2delta 2
Synonyms CACNA2D
Swissprot Q9NY47
Target Background
Calcium channels mediate the entry of calcium ions into the cell upon membrane polarization. This gene encodes the alpha-2/delta subunit of the voltage-dependent calcium channel complex. The complex consists of the main channel-forming subunit alpha-1, and auxiliary subunits alpha-2/delta, beta, and gamma. The auxiliary subunits function in the assembly and membrane localization of the complex, and modulate calcium currents and channel activation/inactivation kinetics. The subunit encoded by this gene undergoes post-translational cleavage to yield the extracellular alpha2 peptide and a membrane-anchored delta polypeptide. This subunit is a receptor for the antiepileptic drug, gabapentin. Mutations in this gene are associated with early infantile epileptic encephalopathy. Single nucleotide polymorphisms in this gene are correlated with increased sensitivity to opioid drugs. Alternative splicing results in multiple transcript variants encoding different isoforms.
Applications
Immunohistochemistry
Predicted cell location: Cell membrane
Positive control: Human colorectal cancer
Recommended dilution: 25-100
The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using ml263357(CACNA2D2 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)
ELISA
Recommended dilution: 5000-10000
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Anti-CACNA2D2 antibody
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