Product overview
Description Anti-BMP5 rabbit polyclonal antibody
Applications ELISA, WB
Immunogen Synthetic peptide of human BMP5
Reactivity Human, Mouse
Content 0.6 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol BMP5
Full name bone morphogenetic protein 5
Synonyms
Swissprot P22003
Target Background
This gene encodes a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. These proteins are synthesized as prepropeptides, cleaved, and then processed into dimeric proteins. This protein may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. This gene is differentially regulated during the formation of various tumors.
Applications
Western blotting
Predicted band size:52 kDa
Positive control:Human lung tissue lysate
Recommended dilution: 200-1000