Product overview
Description Anti-IFNGR1 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Synthetic peptide of human IFNGR1
Reactivity Human
Content 0.4 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol IFNGR1
Full name interferon gamma receptor 1
Synonyms CD119; IFNGR; IMD27A; IMD27B
Swissprot P15260
Target Background
This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection.
Applications
Immunohistochemistry
Predicted cell location: Cell membrane
Positive control: Human prostate cancer
Recommended dilution: 10-50
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using ml263033(IFNGR1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ×200)
Western blotting
Predicted band size:54 kDa
Positive control:Human lung tissue and HEPG2 cell lysates
Recommended dilution: 200-1000