Anti-AGAP4 antibody

Anti-AGAP4 antibody

Cat. No.     JC262835
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-AGAP4 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human AGAP4
Reactivity                 Human
Content                     1.08 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 AGAP4
Full name                 ArfGAP with GTPase domain, ankyrin repeat and PH domain 4
Synonyms    AGAP8; MRIP2; AGAP-4; AGAP-8; CTGLF1; CTGLF5
Swissprot    Q96P64

Target Background
AGAP4(also known as Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 4) is a GTPase activating protein. It is overexpressed in cancer cells, prevents apoptosis and promotes cancer cell invasion. AGAP4 and other AGAP proteins likely function in the secretory pathway, which could explain a link with the invasive behavior of cancer cells. Reliable antibodies would be invaluable for studies of the physiologic function of the proteins and how is may be linked to cancer cell invasive behavior.

Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 20-100    
            
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using ml262835(AGAP4 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)    

ELISA
Recommended dilution: 5000-10000