AGPAT2 Antibody is a Rabbit Polyclonal antibody against AGPAT2. This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Target
AGPAT2
Reactivity
Human, Mouse
Host
Rabbit
Clonality
Polyclonal
Tested Applications
WB, IF/ICC
Recommended dilutions
WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Immunogen
Recombinant protein of human AGPAT2.
Purification
Affinity purified.
Form
Liquid
Isotype
IgG
Conjugation
Unconjugated
Storage
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.