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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -20˚C
- 英文名:
T-cell surface glycoprotein CD3 epsilon chain
- 库存:
详询
- 供应商:
南京莱富赛
- 规格:
详询
host_species:E.coli
purification:>90% by SDS-PAGE
specificity:Human
other_names:T3E,T-cell surface antigen T3/Leu-4 epsilon chain,CD3e
accession_no:P07766
Gene name:CD3E
calculated_mw:
tag info:His
Immunogen Description:CHNDKNIGGDEDDKNIGSDEDHLSL
formulation:50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
storage:Store at -20C. (Avoid repeated freezing and thawing.)
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
background:The CD3 complex mediates signal transduction, resulting in T-cell activation and proliferation. Required for normal immune responses (PubMed:15546002, PubMed:8490660).
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文献和实验T-Cell Activation Using mAb to CD3
in clonal expansion of T cells upregulation of activation markers on the cell surface differentiation into effector cells induction of cytotoxicity or cytokine secretion induction of apoptosis
Flow Cytometric Detection of Cytoplasmic and Surface CD3-ε Expression in Developing T Cells
8. However, the acquisition of a functional T-cell antigen receptor (TCR)/CD3 complex is perhaps the most significant of the events that take place during early thymocyte development. This multisubunit complex consists of two disulfide-linked variant TCRα/β (or TCRγ/δ) chains
cell receptors, most B cell lymphomas Micro images: CD3 epsilon-testicular NK/T cell lymphoma (figure 3D) Micro images (AJSP subscribers): achalasia, post-transplant lymphoproliferative disease in liver References: AJSP 2001;25:1413
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