- 询价
- Signalway Antibody
- USA
- AP79125
- 2025年07月16日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at -20˚C
- 英文名：
Cofilin-1
- 库存：
详询
- 供应商：
南京莱富赛
- 规格：
详询
host_species:E.coli
purification:>90% by SDS-PAGE
specificity:Rat
other_names:Cofilin, non-muscle isoform
accession_no:P45592
Gene name:Cfl1
calculated_mw:18.15
tag info:His
Immunogen Description:2-166AA
formulation:50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
storage:Store at -20C. (Avoid repeated freezing and thawing.)
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
background:Binds to F-actin and exhibits pH-sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation. Required for neural tube morphogenesis and neural crest cell migration.
产品详细信息请点击：Cofilin-1
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文献和实验检测自噬 marker LC3B（~14-17 kDa），则应避免使用 Cofilin 或 Cyclophilin B（~20 kDa）这些分子量与目标蛋白接近的内参蛋白。√ 表达水平：选择的内参蛋白需要在待测样本中是高表达的。常用的内参蛋白是由管家基因高表达的，是细胞发育和维持细胞活力所必须的。例如，细胞核的内参蛋白 PCNA，在 DNA S 期表达，因此对于非增殖细胞不推荐使用。√ 表达因素：选择表达不受实验变量影响的内参，例如，细胞应激反应中 HSP60 会表达上调，因此在研究细胞应激实验中
Chemokine Receptor Signaling and HIV Infection
depolymerization factor, cofilin, to support viral latent infection of resting CD4 T cells. Activation of cofilin promotes the cortical actin dynamics that are critical for viral intracellular migration across the static cortical actin barrier in resting T cells.
Figure a0.1B.1 A sample FASTA file that contains the sequences for two homologous proteins, actophorin and yeast cofilin. Note that a greater‐than sign (>) designates the beginning of each entry and that each of the lines of sequence contains
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