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- 详细信息
- 询价记录
- 文献和实验
- 技术资料
- 保存条件:
Store at -20˚C
- 英文名:
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
- 库存:
详询
- 供应商:
南京莱富赛
- 规格:
详询
host_species:E.coli
purification:>90% by SDS-PAGE
specificity:Human
other_names:2.4.99.20,2'-phospho-ADP-ribosyl cyclase,2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase,2'-phospho-cyclic-ADP-ribose transferase,ADP-ribosyl cyclase 1,Cyclic ADP-ribose hydrolase 1,T10,ADPRC 1,cADPr hydrolase 1,CD38
accession_no:P28907
Gene name:CD38
calculated_mw:28.38
tag info:His
Immunogen Description:43-300AA
formulation:50mM NaH2PO4, 500mM NaCl Buffer with 500mM Imidazole,10%glycerol(PH8.0)
storage:Store at -20C. (Avoid repeated freezing and thawing.)
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
background:Synthesizes the second messagers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
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文献和实验Cyclic ADP-ribose (cADPR) is a novel second messenger that releases calcium from intracellular stores. Although first shown to release calcium in the sea urchin egg, cADPR has been shown since to be active in a variety of cells and tissues
Determination of NOS Activity Using Cyclic-GMP Formation
which diffuses from the originator cell to affect other “target” cells in a paracrine manner. NO effects on cells include adenine diphosphate (ADP)-ribosylation and nitrosation/nitration of proteins, and the activation of soluble guanylyl cyclase (GC-S) to form
Endocrinol 173(3): 467-474. 6. Zheng, X., L. Ying, et al. (2011). "Role of sulfhydryl-dependent dimerization of soluble guanylyl cyclase in relaxation of porcine coronary artery to nitric oxide." Cardiovasc Res 90(3): 565-572. 7. Tsai, E. J
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