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- Signalway Antibody
- USA
- AP78215
- 2025年07月11日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
Store at -20˚C
- 英文名：
Recombinant Human Acyl-CoA desaturase(SCD)
- 库存：
详询
- 供应商：
南京莱富赛
- 规格：
详询
host_species:in vitro E.coli expression system
purification:Greater than 85% as determined by SDS-PAGE.
other_names:Delta(9)-desaturase Short name: Delta-9 desaturase Fatty acid desaturase Stearoyl-CoA desaturase1 Short name: hSCD1
accession_no:O00767
calculated_mw:44.3 kDa
tag info:N-terminal 10xHis-tagged
Immunogen Description:Expression Region:1-359aa
Sequence Info:Full Length
formulation:Tris-based buffer50% glycerol
storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃,-80℃. The shelf life of lyophilized form is 12 months at -20℃,-80℃.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
background:Stearyl-CoA desaturase that utilizes O2 and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. Catalyzes the insertion of a cis double bond at the delta-9 position into fatty acyl-CoA substrates including palmitoyl-CoA and stearoyl-CoA. Gives rise to a mixture of 16:1 and 18:1 unsaturated fatty acids. Plays an important role in lipid biosynthesis. Plays an important role in regulating the expression of genes that are involved in lipogenesis and in regulating mitochondrial fatty acid oxidation. Plays an important role in body energy homeostasis. Contributes to the biosynthesis of membrane phospholipids, cholesterol esters and triglycerides
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., Gibson, W.T., Fievet, C., Vance, J.E., Staels, B., and Hayden, M.R. 2008. Absence of stearoyl‐CoA desaturase‐1 ameliorates features of the metabolic syndrome in LDLR‐deficient mice. J. Lipid Res. 49:217‐229.
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