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Recombinant Human C-X-C chemok

ine receptor type 4(CXCR4)
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  • 询价
  • Signalway Antibody已认证
  • USA
  • AP78197
  • 2025年07月15日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      Store at -20˚C

    • 英文名

      Recombinant Human C-X-C chemokine receptor type 4(CXCR4)

    • 库存

      详询

    • 供应商

      南京莱富赛

    • 规格

      详询

    host_species:in vitro E.coli expression system

    purification:Greater than 90% as determined by SDS-PAGE.

    other_names:FB22 Fusin HM89 LCR1 Leukocyte-derived seven transmembrane domain receptor

    accession_no:P61073

    calculated_mw:44.2 kDa

    tag info:N-terminal 6xHis-tagged

    Immunogen Description:Expression Region:1-356aa
    Sequence Info:Full?Length?of?Isoform?2

    formulation:Tris-based buffer50% glycerol

    storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃,-80℃. The shelf life of lyophilized form is 12 months at -20℃,-80℃.
    Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

    background:Receptor for the C-X-C chemokine CXCL12,SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1,MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and,or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival. (Microbial infection) Acts as a coreceptor (CD4 being the primary receptor) for human immunodeficiency virus-1,HIV-1 X4 isolates and as a primary receptor for some HIV-2 isolates. Promotes Env-mediated fusion of the virus. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes

    产品详细信息请点击:Recombinant Human C-X-C chemokine receptor type 4(CXCR4)

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