Recombinant Human Hepatitis B

host_species:E.coli

purification:Greater than 90% as determined by SDS-PAGE.

other_names:Hepatitis B virus X-interacting protein

accession_no:O43504

calculated_mw:36.6 kDa

tag info:N-terminal GST-tagged

Immunogen Description:Expression Region:1-91aa
Sequence Info:Full Length

formulation:Tris-based buffer50% glycerol

storage:The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃,-80℃. The shelf life of lyophilized form is 12 months at -20℃,-80℃.
Notes:Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

background:As part of the Ragulator complex it is involved in amino acid sensing and activation of mTORC1, a signaling complex promoting cell growth in response to growth factors, energy levels, and amino acids. Activated by amino acids through a mechanism involving the lysosomal V-ATPase, the Ragulator functions as a guanine nucleotide exchange factor activating the small GTPases Rag. Activated Ragulator and Rag GTPases function as a scaffold recruiting mTORC1 to lysosomes where it is in turn activated. When complexed to BIRC5, interferes with apoptosome assembly, preventing recruitment of pro-caspase-9 to oligomerized APAF1, thereby selectively suppressing apoptosis initiated via the mitochondrial,cytochrome c pathway. Down-regulates hepatitis B virus (HBV) replication.

产品详细信息请点击：Recombinant Human Hepatitis B virus X-interacting protein(HBXIP)