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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Store at -20˚C
- 英文名:
Recombinant Mouse β-Nerve Growth Factor,β-NGF (Ser122-Gly241)
- 库存:
详询
- 供应商:
南京莱富赛
- 规格:
详询
host_species:E.coli
purification:Greater than 95% as determined by reducing SDS-PAGE.
specificity:Mouse
accession_no:P01139
calculated_mw:13.5kDa
formulation:Lyophilized from a 0.2 μm filtered solution of 20mM Tris,150mM NaCl,pH8.0.
reconstitution:Always centrifuge tubes before opening. Do not mix by vortex or pipetting.
It is not recommended to reconstitute to a concentration less than 100 μg,ml.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
storage:Lyophilized protein should be stored at < -20C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20C for 3 months.
产品详细信息请点击:Recombinant Mouse β-Nerve Growth Factor,β-NGF (Ser122-Gly241)
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文献和实验The transforming growth factor (TGF)-β signaling pathway plays a critical role in breast cancer development and progression. Limited data from human studies, however, are currently available to link biomarkers in this pathway directly to the risk
的蛋白质,由两个亚单位构成的二合体或多合体显有活性。另一方面,瓦恩(S.Varon,1967)认为,活性成分是分子量约为14万的蛋白质,具有分子量约为3万的α、β、γ三种亚单位,仅β表现有NGF活性。将精制的NGF注射于鸡胚或初生小鼠,则发育中的感觉和交感神经节细胞的有丝分裂频率增高,细胞数增加,神经节体积显著增大。将兔的NGF抗血清注射于怀孕小鼠或初生小鼠等哺乳类,则生出来的幼体及实验个体的交感神经细胞出现选择性的坏死(免疫去交感)。对于培养中的神经节,其促进纤维生长和再生效果也是显著
Production of Recombinant Neurotrophic Factors
The introduction of recombinant technology has dramatically influenced progress in the studies of many proteins and systems. In the areas of neurochemistry and neurobiology, perhaps the most notable effect has been on work with nerve growth
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