Anti-RPS6KB2 antibody

Anti-RPS6KB2 antibody

Cat. No.     JC262006
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-RPS6KB2 rabbit polyclonal antibody
Applications        ELISA, WB, IHC 
Immunogen               Synthetic peptide of human RPS6KB2
Reactivity                 Human, Mouse
Content                     0.3 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 RPS6KB2
Full name                 ribosomal protein S6 kinase, 70kDa, polypeptide 2
Synonyms    KLS; SRK; S6K2; STK14B; p70S6Kb; P70-beta; S6K-beta2; P70-beta-1; P70-beta-2; p70(S6K)-beta
Swissprot    Q9UBS0

Target Background
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.

Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human prostate cancer
Recommended dilution: 25-100    
            
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using ml262006(RPS6KB2 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)    
Western blotting
Predicted band size:53 kDa
Positive control:Hela and K562 cells 
Recommended dilution: 200-1000