GCP170; GOLGA 3; GOLGA3; Golgi autoantigen; Golgi complex associated protein of 170 kDa; Golgi complex-associated protein of 170 kD; Golgi membrane associated protein; Golgi peripheral membrane protein; Golgin 160; Golgin subfamily a 3; HGNC:4426; Male enhanced antigen 2; MEA2; SY2/SY10 protein; GOGA3_HUMAN.
规格价格
100ul/2980元 购买 大包装/询价
说 明 书
100ul
研究领域
细胞生物 信号转导 转运蛋白
抗体来源
Rabbit
克隆类型
Polyclonal
交叉反应
Human, Mouse, Rat, Cow, Rabbit, Sheep,
产品应用
ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量
167kDa
性 状
Lyophilized or Liquid
浓 度
1mg/ml
免 疫 原
KLH conjugated synthetic peptide derived from human GOLGA3/Golgin 160
亚 型
IgG
纯化方法
affinity purified by Protein A
储 存 液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍
background: The Golgi apparatus consists of a series of stacked, flattened membrane stacks called cisternae that are involved in the transport of lipids and proteins in the secretory pathway and are important for Golgi-microtubule interaction. Golgin 160 is a 1,498 amino acid protein that localizes to both the cytoplasm and to the Golgi apparatus and contains a series of coiled-coil domains. Expressed in a variety of tissues, including heart, liver, testis, kidney, lung and salivary gland, golgin 160 functions as a homodimer that interacts with GOLGA7 and is thought to be involved in maintaining Golgi structure and may play a role in nuclear transport and Golgi apparatus localization. Multiple isoforms of golgin 160 exist due to alternative splicing events.
Function: GOLGA3 is a member of the golgin family of proteins which are localized to the Golgi. It has been postulated to play a role in nuclear transport and Golgi apparatus localization.
Subunit: Homodimer. Interacts with GOLGA7. Isoform 1 interacts with GOPC while isoform 3 does not.
Subcellular Location: Cytoplasmic and Golgi Apparatus.
Tissue Specificity: Expressed in all tissues tested. Expressed in liver, testis, lung, heart, salivary gland and kidney.
Post-translational modifications: Cleaved by caspases in apoptotic cells.
Database links:
Entrez Gene: 2802 Human
Omim: 602581 Human
SwissProt: Q08378 Human
Unigene: 507333 Human
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.