ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
分 子 量
255kDa
细胞定位
细胞膜
性 状
Lyophilized or Liquid
浓 度
1mg/ml
免 疫 原
KLH conjugated synthetic peptide derived from human NAV3
亚 型
IgG
纯化方法
affinity purified by Protein A
储 存 液
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存条件
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
产品介绍
background: May regulate IL2 production by T-cells. May be involved in neuron regeneration.
Function: May regulate IL2 production by T-cells. May be involved in neuron regeneration.
Subcellular Location: Nucleus outer membrane.
Tissue Specificity: Highly expressed in brain. Expressed at low levels in heart and placenta. Present in activated T-cells but not in resting T-cells (at protein level). Down-regulated in primary neuroblastoma.
DISEASE: Note=A chromosomal aberration disrupting NAV3 has been found in patients with Sezary syndrome. Translocation t(12;18)(q21;q21.2).
Similarity: Sequence similarities; Belongs to the Nav/unc-53 family. Contains 1 CH (calponin-homology) domain.
Database links:
Entrez Gene: 89795 Human
Entrez Gene: 260315 Mouse
Entrez Gene: 314814 Rat
Omim: 611629 Human
SwissProt: Q8IVL0 Human
SwissProt: Q80TN7 Mouse
Unigene: 655301 Human
Unigene: 225050 Mouse
Unigene: 394160 Mouse
Unigene: 461280 Mouse
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.