- 询价
- Signalway Antibody
- USA
- 13091
- 2026年01月24日
- WB
- Rabbit
- Hu, Ms, Rt
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
A synthesized peptide derived from human Interferon-γ Receptor 1 around the phosphorylation site of Tyr457
- 形态：
liquid
- 保存条件：
Store at -20˚C
- 克隆性：
Polyclonal
- 适应物种：
Hu, Ms, Rt
- 宿主：
Rabbit
- 应用范围：
WB
- 浓度：
1mg/ml
- 抗体英文名：
Interferon-γ Receptor 1 (Phospho-Tyr457) Antibody
clonality:Polyclonal
specificity:Phospho-Interferon-γ Receptor 1 (Phospho-Tyr457) Antibody detects endogenous levels of Interferon-γ Receptor 1 only when phosphorylated at Tyr457
other_names:Antiviral Protein Type II; Antiviral protein, type 2; AVP type II; AVP, type 2; CD 119; CD119; CD119 antigen; CDw119; FLJ45734; IFN gamma R alpha; IFN gamma R; IFN gamma R1; IFN-gamma receptor 1; IFN-gamma-R1; IFNG R1; IFNGR 1; IFNGR; IFNGR1; Immune interferon receptor 1; Immune interferon receptor for; INGR1_HUMAN; Interferon gamma receptor 1; Interferon gamma receptor alpha chain; Interferon gamma receptor alpha chain precursor; accession_no:Swiss-Prot#:P15260
NCBI Gene ID:3459
产品详细信息请点击：Interferon-γ Receptor 1 (Phospho-Tyr457) Antibody
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文献和实验Characterisation of Viral Proteins that Inhibit Toll-Like Receptor Signal Transduction
Toll-like receptor (TLR) signalling involves five TIR adapter proteins, which couple to downstream protein kinases that ultimately lead to the activation of transcription factors such as nuclear factor-κB (NF-κB) and members of the interferon
Bispecific Antibody MDX-210 for Treatment of Advanced Ovarian and Breast Cancer
immune effector mechanisms, such as complement fixation and antibody-dependent cell-mediated cytotoxicity (ADCC) in humans. Additionally, although humanized MAbs are being developed, when used therapeutically their immunological effectiveness
FcR阻断剂，让流式实验中的干扰无处遁形 说到Fc阻断，就不得不提到抗体。抗体的结构分为Fab和Fc段，Fab段是与目标分子特异性结合的区域，Fc段是Ig与效应分子或者细胞相互作用的部位[1]（图1）。Fc受体（Fragment Crystallizable Receptor，FcR）是免疫调节受体中非常重要的受体，主要在先天免疫细胞上表达，能被抗体的Fc段识别并结合，从而引发免疫应答。 图1：抗体结构 为什么要做Fc阻断? 在细胞学实验中，正确区分阳性和阴性细胞十分重要。获得良好
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