Product overview Description Anti-CAGE1 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human CAGE1
Reactivity Human
Content 0.3 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information Symbol CAGE1
Full name cancer antigen 1
Synonyms CT3; CT95; CTAG3; bA69L16.7
Swissprot Q8TC20
Target Background CAGE1, also known as CT3; CT95; CTAG3; bA69L16.7, is a 639-amino acid protein. It shares 76% sequence identity with a monkey homolog. RT-PCR analysis detected testis-specific expression among normal tissues and wide expression among various cancer tissues and cancer cell lines including those from cervical, melanoma, hepatic, renal, myeloma, and breast cancers. CTAG3 was overexpressed in cancer tissues compared with surrounding noncancerous tissues. Transfection experiments with a GFP-CTAG3 construct indicated a predominantly nuclear localization.