Anti-SERPINA9 antibody

Anti-SERPINA9 antibody

Cat. No.     JC261394
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-SERPINA9 rabbit polyclonal antibody
Applications        ELISA, WB, IHC 
Immunogen               Synthetic peptide of human SERPINA9
Reactivity                 Human
Content                     0.8 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 SERPINA9
Full name                 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9
Synonyms    GCET1; SERPINA11; SERPINA11b
Swissprot    Q86WD7

Target Background
Serpin A9 also known as centerin or GCET1 is a protein that in humans is encoded by the SERPINA9 gene located on chromosome 14q32.1.[1] Serpin A9 is a member of the serpin family of serine protease inhibitors. The expression of SERPINA9 is restricted to germinal center B cells and lymphoid malignancies. SERPINA9 is likely to function in vivo in the germinal center as an efficient inhibitor of trypsin-like proteases. Highly expressed in normal germinal center (GC) B-cells and GC B-cell-derived malignancies.

Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human cervical cancer
Recommended dilution: 25-100    Predicted cell location: Cytoplasm
Positive control: Human brain
Recommended dilution: 25-100
            
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using ml261394(SERPINA9 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ×200)    The image on the left is immunohistochemistry of paraffin-embedded Human brain  tissue using ml261394(SERPINA9 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: ×200)
Western blotting
Predicted band size:47 kDa
Positive control:293T and 231 cells, U937 and Raji cells 
Recommended dilution: 500-2000