Product overview
Description Anti-EHMT2 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human EHMT2
Reactivity Human, Mouse
Content 0.48 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol EHMT2
Full name euchromatic histone lysine methyltransferase 2
Synonyms G9A; BAT8; GAT8; NG36; KMT1C; C6orf30
Swissprot Q96KQ7
Target Background
This gene encodes a methyltransferase that methylates lysine residues of histone H3. Methylation of H3 at lysine 9 by this protein results in recruitment of additional epigenetic regulators and repression of transcription. This gene was initially thought to be two different genes, NG36 and G9a, adjacent to each other in the HLA locus. Alternative splicing results in multiple transcript variants.
Applications
Immunohistochemistry
Predicted cell location: Nucleus
Positive control: Human esophagus cancer
Recommended dilution: 25-100 Predicted cell location: Nucleus
Positive control: Human liver cancer
Recommended dilution: 25-100
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using ml263844(EHMT2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using ml263844(EHMT2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)