Anti-LOXL4 antibody

Anti-LOXL4 antibody

Cat. No.     JC122186        
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-LOXL4 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Fusion protein of human LOXL4
Reactivity                 Human, Mouse
Content                     0.5 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-LOXL4 antibody
Target information
Symbol                 LOXL4
Full name                 lysyl oxidase-like 4
Synonyms    LOXC
Swissprot    Q96JB6

Target Background
This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.

Anti-LOXL4 antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human liver cancer
Recommended dilution: 50-200    Predicted cell location: Cytoplasm
Positive control: Human thyroid cancer
Recommended dilution: 50-200