Product overview
Description Anti-MKKS rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human MKKS
Reactivity Human
Content 0.4 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol MKKS
Full name McKusick-Kaufman syndrome
Synonyms KMS; MKS; BBS6; HMCS
Swissprot Q9NPJ1
Target Background
This gene encodes a protein which shares sequence similarity with other members of the type II chaperonin family. The encoded protein is a centrosome-shuttling protein and plays an important role in cytokinesis. This protein also interacts with other type II chaperonin members to form a complex known as the BBSome, which involves ciliary membrane biogenesis. This protein is encoded by a downstream open reading frame (dORF). Several upstream open reading frames (uORFs) have been identified, which repress the translation of the dORF, and two of which can encode small mitochondrial membrane proteins.