Anti-ARFGAP1 antibody

Anti-ARFGAP1 antibody

Cat. No.     JC121677        
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-ARFGAP1 rabbit polyclonal antibody
Applications        ELISA, WB 
Immunogen               Fusion protein of human ARFGAP1
Reactivity                 Human, Mouse
Content                     0.3 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-ARFGAP1 antibody
Target information
Symbol                 ARFGAP1
Full name                 ADP-ribosylation factor GTPase activating protein 1
Synonyms    ARF1GAP; HRIHFB2281
Swissprot    Q8N6T3

Target Background
The protein encoded by this gene is a GTPase-activating protein (GAP) which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1 (ARF1). The encoded protein promotes hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Two transcript variants encoding different isoforms have been found for this gene.

Anti-ARFGAP1 antibody
Applications
Western blotting
Predicted band size:45 kDa
Positive control:293T, PC3 and NIH/3T3 cells 
Recommended dilution: 1000-5000