Anti-BCL2L12 antibody

Anti-BCL2L12 antibody

Cat. No.     JLC220154
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-BCL2L12 rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Fusion protein of human BCL2L12
Reactivity                 Human
Content                     0.2 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification



Target information
Symbol                 BCL2L12
Full name                 BCL2-like 12 (proline rich)
Synonyms    
Swissprot    Q9HB09

Target Background
This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants