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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Membranes from a human melanoma metastasis
- 亚型:
IgG2b
- 形态:
Liquid
- 保存条件:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
- 克隆性:
Monoclonal
- 标记物:
Unconjugated
- 适应物种:
Human, Horse
- 保质期:
12 months from the shipping date of the product.
- 抗原来源:
Human
- 目录编号:
GTX34835
- 级别:
Primary Antibodies
- 库存:
Available
- 供应商:
GeneTex
- 宿主:
Mouse
- 应用范围:
IHC-P, Protein Array
- 浓度:
0.2 mg/ml (Please refer to the vial label for the specific concentration.)
- 靶点:
We do not recommend use of this product for Rat.
- 抗体英文名:
Melanoma gp100 antibody [NKI-beteb]
- 抗体名:
Melanoma gp100 抗体 [NKI-beteb]
- 规格:
100 μg
IHC-P analysis of human melanoma tissue using GTX34835 Melanoma gp100 antibody [NKI-beteb].
Analysis of Protein Array containing more than 19,000 full-length human proteins using PMEL/gp100 Mouse Monoclonal Antibody (NKI-beteb). Z-. Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD’s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD’s) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.
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文献和实验Nat Med:个体化肿瘤疫苗突破,特异性 T 细胞持续 4.5 年,患者存活率 100%
方面的结果如何呢? 2021 年 1 月 21 日,来自美国 Dana-Farber 癌症研究所的 Catherine J. Wu 团队在 Nature Medicine 上发表了题为 Personal neoantigen vaccines induce persistent memory T cell responses and epitope spreading in patients with melanoma 的文章 [1],向世界宣布了一项令人兴奋的临床试验结果:8 名恶性黑色素瘤患者
Nature 综述导读:FDA 批准第 100 个抗体药物!抗体药物的研究方向在哪里?
批准了第 50 种抗体,距离第一个抗体已经过去了 29 年。2021 年 4 月,随着葛兰素史克 PD1 阻断剂 dostarlimab 的批准,抗体药物仅用了 6 年多的时间就达到了 100 个,进入了「百抗」新时代(图五)。 图五 Nature Reviews Drug Discovery 20, 10 (2021) 上面提到的 100 个抗体并不是单纯经典的单克隆的裸抗体(naked antibody),其中也包括了抗体片段已经工程化修饰抗体的各种偶联形式。其中包括有抗体药物偶联(ADC
【转帖】Top 100 proteomics publications
Top 100 proteomics publications ----From Ion Channel Media Group:ttp://www.ionchannelmedia.com/websites.php 1. Gavin et al. (2006) Proteome survey reveals modularity of the yeast cell machinery. Nature 2. Bonetta et al. (2006) Protein
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