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文献和实验of human dendritic cell (DC) development. While the amount of data on the different subsets of conventional DCs (cDCs) and plasmacytoid DCs (pDCs) rapidly increases in mice (3, 4), the developmental stages of different DC subsets in humans remain poorly
Human Intestinal Dendritic Cell Isolation
bowel than in normal controls. The isolation of dendritic (DC) cells from human intestinal tissue is associated with many of the problems encountered in the mouse, for example, low cell numbers and the paucity of specific cell surface markers. Particular
Plasmacytoid Dendritic Cells in Tolerance
distribution. Murine plasmacytoid DC (pDC) represent a distinctive DC population and are characterized by the expression of CD11c, B220, Gr-1, CD45RA, Ly49Q, BST2, and siglec-H on the cell surface. PDC act as immunogenic cell sentinels by secreting large
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