- 询价
- gelatins
- JLC260957
- 上海
- 2025年07月13日
- Rabbit
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- 详细信息
- 技术资料
- 供应商：
江西江蓝纯生物试剂有限公司
- 库存：
大量
- 克隆性：
多克隆
- 保质期：
1年
- 抗体英文名：
Anti-BCR antibody
- 宿主：
Rabbit
- 浓度：
0.5 mg/ml
- 保存条件：
-20°C
- 规格：
25 μl/100 μl/200 μl
Anti-BCR antibody
Cat. No. JLC260957
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-BCR rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human BCR
Reactivity Human, Mouse
Content 0.5 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol BCR
Full name breakpoint cluster region
Synonyms ALL; CML; PHL; BCR1; D22S11; D22S662
Swissprot P11274
Target Background
A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human gasrtic cancer
Recommended dilution: 25-100 Predicted cell location: Cytoplasm
Positive control: Human colon cancer
Recommended dilution: 25-100
The image on the left is immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using ml260957(BCR Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using ml260957(BCR Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: ×200)
ELISA
Recommended dilution: 1000-2000
Cat. No. JLC260957
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-BCR rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human BCR
Reactivity Human, Mouse
Content 0.5 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol BCR
Full name breakpoint cluster region
Synonyms ALL; CML; PHL; BCR1; D22S11; D22S662
Swissprot P11274
Target Background
A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human gasrtic cancer
Recommended dilution: 25-100 Predicted cell location: Cytoplasm
Positive control: Human colon cancer
Recommended dilution: 25-100
The image on the left is immunohistochemistry of paraffin-embedded Human gasrtic cancer tissue using ml260957(BCR Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using ml260957(BCR Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: ×200)
ELISA
Recommended dilution: 1000-2000
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Anti-BCR antibody
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