Product overview
Description Anti-PTGDR2 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Synthetic peptide of human PTGDR2
Reactivity Human, Mouse, Rat
Content 1.08 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol PTGDR2
Full name prostaglandin D2 receptor 2
Synonyms DP2; DL1R; CD294; CRTH2; GPR44
Swissprot Q9Y5Y4
Target Background
This gene encodes a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells. This protein is a prostaglandin D2 receptor that mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of this gene have been associated with asthma susceptibility.