Anti-CASP14 antibody

Anti-CASP14 antibody

Cat. No.     JC120081        
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-CASP14 rabbit polyclonal antibody
Applications        ELISA, WB 
Immunogen               Fusion protein of human CASP14
Reactivity                 Human
Content                     0.7 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Anti-CASP14 antibody
Target information
Symbol                 CASP14
Full name                 caspase 14, apoptosis-related cysteine peptidase
Synonyms    
Swissprot    P31944

Target Background
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.

Anti-CASP14 antibody
Applications
Western blotting
Predicted band size:28 kDa
Positive control:Jurkat, A431, A549 and A375 cells 
Recommended dilution: 500-2000