Product overview
Description Anti-EGF rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human EGF
Reactivity Human
Content 0.7 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-EGF antibody Target information
Symbol EGF
Full name epidermal growth factor
Synonyms URG, HOMG4
Swissprot P01133
Target Background
This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants
Anti-EGF antibody Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human cervical cancer
Recommended dilution: 50-200