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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
上海机纯实业有限公司
- 库存:
大量
- 克隆性:
多克隆
- 保质期:
12个月
- 抗体英文名:
Anti-AKT1 antibody
- 宿主:
Rabbit
- 适应物种:
人/动物/植物
- 应用范围:
ELISA, WB
- 浓度:
0.4 mg/ml
- 保存条件:
-20°C
- 规格:
25 μl/100 μl/200 μl
Cat. No. JC120056
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-AKT1 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human AKT1
Reactivity Human, Mouse, Rat
Content 0.4 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Anti-AKT1 antibody
Target information
Symbol AKT1
Full name V-akt murine thymoma viral oncogene homolog 1
Synonyms AKT, PKB, RAC, PRKBA, PKB-ALPHA, RAC-ALPHA
Swissprot P31749
Target Background
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene.
Anti-AKT1 antibody
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm, Nucleus
Positive control: Human colon cancer
Recommended dilution: 25-100 Predicted cell location: Cytoplasm, Nucleus
Positive control: Human tonsil
Recommended dilution: 25-100
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文献和实验jixianxiu1982 各位大侠,有谁知道AKT1的基因序列呀,我找了好久没找到。 doctormy 人类AKT1序列: http://www.ncbi.nlm.nih.gov/nuccore/33875493 jixianxiu1982 谢谢doctormy大侠 jixianxiu1982 我还想继续知道其中PH结构域的基因序列,该怎么找
a simple ELISA method to detect human anti-antibody response.
Purification Of Anti Peptide Antibody
antibody that could contribute to staining background. The proportion in each pool varies with the peptide immunogen. The quality of the anti-peptide serum seems to increase with multiple boosts - the first bleed may be feeble.










