- 询价
- gelatins
- JLC260469
- 上海
- 2025年07月15日
- Rabbit
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- 详细信息
- 技术资料
- 供应商：
江西江蓝纯生物试剂有限公司
- 库存：
大量
- 克隆性：
多克隆
- 保质期：
1年
- 抗体英文名：
Anti-GCH1 antibody
- 宿主：
Rabbit
- 浓度：
0.3 mg/ml
- 保存条件：
-20°C
- 规格：
25 μl/100 μl/200 μl
Anti-GCH1 antibody
Cat. No. JLC260469
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-GCH1 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Synthetic peptide of human GCH1
Reactivity Human
Content 0.3 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol GCH1
Full name GTP cyclohydrolase 1
Synonyms GCH, DYT5, DYT14, DYT5a, GTPCH1, HPABH4B, GTP-CH-1
Swissprot P30793
Target Background
This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme.
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human breast cancer
Recommended dilution: 5-20
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using ml260469(GCH1 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: ×200)
Western blotting
Predicted band size:28 kDa
Positive control:Human fetal liver tissue
Recommended dilution: 500-2000
Gel: 12%SDS-PAGE
Lysate: 60 μg
Lane: Human fetal liver tissue
Primary antibody: ml260469(GCH1 Antibody) at dilution 1/200
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
Exposure time: 15 seconds
ELISA
Recommended dilution: 1000-5000
Cat. No. JLC260469
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-GCH1 rabbit polyclonal antibody
Applications ELISA, WB, IHC
Immunogen Synthetic peptide of human GCH1
Reactivity Human
Content 0.3 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol GCH1
Full name GTP cyclohydrolase 1
Synonyms GCH, DYT5, DYT14, DYT5a, GTPCH1, HPABH4B, GTP-CH-1
Swissprot P30793
Target Background
This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described; however, not all variants give rise to a functional enzyme.
Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human breast cancer
Recommended dilution: 5-20
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using ml260469(GCH1 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: ×200)
Western blotting
Predicted band size:28 kDa
Positive control:Human fetal liver tissue
Recommended dilution: 500-2000
Gel: 12%SDS-PAGE
Lysate: 60 μg
Lane: Human fetal liver tissue
Primary antibody: ml260469(GCH1 Antibody) at dilution 1/200
Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution
Exposure time: 15 seconds
ELISA
Recommended dilution: 1000-5000
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Anti-GCH1 antibody
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