FITC标记的磷酸化细胞周期末期促进复合蛋白APC1抗体

FITC标记的磷酸化细胞周期末期促进复合蛋白APC1抗体

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  • ¥2980
  • LMAI Bio
  • LM-12482R-FITC
  • 中国/美国/欧洲
  • 2025年07月12日
  • ICC=1:50-200 IF=1:50-200
  • Human, Mouse, Rat, Chicken,
  • Human, Mouse, Rat, Chicken,
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    • 详细信息
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 靶点

      详见说明书

    • 级别

      1

    • 目录编号

      LM-12482R-FITC

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      Anti-phospho-APC1 (Ser688)/FITC

    • 抗体名

      Anti-phospho-APC1 (Ser688)/FITC

    • 标记物

      FITC标记

    • 宿主

      Human, Mouse, Rat, Chicken,

    • 适应物种

      Human, Mouse, Rat, Chicken,

    • 免疫原

      详见说明书

    • 亚型

      IGg

    • 形态

      粉末、液体、冻干粉

    • 应用范围

      ICC=1:50-200 IF=1:50-200

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      100ul

    FITC标记的磷酸化细胞周期末期促进复合蛋白APC1抗体
    英文名称 Anti-phospho-APC1 (Ser688)/FITC
    中文名称 FITC标记的磷酸化细胞周期末期促进复合蛋白APC1抗体
    别    名 phospho-ANAPC1(Ser688); Apc1 (phospho S688); ANAPC 1; ANAPC1; Anaphase promoting complex subunit 1; anaphase-promoting complex 1 (meiotic checkpoint regulator); Anaphase-promoting complex subunit 1; Apc 1; APC1; APC1_HUMAN; Cyclosome subunit 1; MCPR; Meiotic checkpoint regulator; Mitotic checkpoint regulator; Protein Tsg 24; Protein Tsg24; Testis-specific gene 24 protein; TSG 24; TSG24.  
    规格价格 100ul/2980元 购买        大包装/询价
    说 明 书 100ul  
    产品类型 磷酸化抗体 
    研究领域 细胞生物  免疫学  信号转导  泛素  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Chicken, 
    产品应用 ICC=1:50-200 IF=1:50-200  
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 215kDa
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthesised phosphopeptide derived from human APC1 around the phosphorylation site of Ser688
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    产品介绍 background:
    This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011].

    Function:
    Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.

    Subunit:
    The APC/C is composed of at least 12 subunits. 

    Post-translational modifications:
    Phosphorylated. Phosphorylation on Ser-355 occurs specifically during mitosis.

    Similarity:
    Belongs to the APC1 family.
    Contains 4 PC repeats. 

    Database links:

    Entrez Gene: 64682 Human

    Entrez Gene: 535565 Cow

    Entrez Gene: 475750 Dog

    Entrez Gene: 17222 Mouse

    Omim: 608473 Human

    SwissProt: E1BAB6 Cow

    SwissProt: E2RLM2 Dog

    SwissProt: Q9H1A4 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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