FITC标记的ASCL2蛋白抗体

FITC标记的ASCL2蛋白抗体

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  • ¥2980
  • LMAI Bio
  • LM-12349R-FITC
  • 中国/美国/欧洲
  • 2025年07月12日
  • ICC=1:50-200 IF=1:50-200
  • Human, Mouse, Rat, Chicken, Dog, Pig, Cow,
  • Human, Mouse, Rat, Chicken, Dog, Pig, Cow,
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    • 详细信息
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 靶点

      详见说明书

    • 级别

      1

    • 目录编号

      LM-12349R-FITC

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      Anti-ASCL2/FITC

    • 抗体名

      Anti-ASCL2/FITC

    • 标记物

      FITC标记

    • 宿主

      Human, Mouse, Rat, Chicken, Dog, Pig, Cow,

    • 适应物种

      Human, Mouse, Rat, Chicken, Dog, Pig, Cow,

    • 免疫原

      详见说明书

    • 亚型

      IGg

    • 形态

      粉末、液体、冻干粉

    • 应用范围

      ICC=1:50-200 IF=1:50-200

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      100ul

    FITC标记的ASCL2蛋白抗体
    英文名称 Anti-ASCL2/FITC
    中文名称 FITC标记的ASCL2蛋白抗体
    别    名 Achaete scute complex like 2; Achaete scute homolog 2; achaete-scute complex-like 2; Achaete-scute homolog 2; ASCL2; ASCL2_HUMAN; ASH-2; Ash2; bHLHa45; Class A basic helix-loop-helix protein 45; HASH2; Mash2.  
    规格价格 100ul/2980元 购买        大包装/询价
    说 明 书 100ul  
    研究领域 细胞生物  发育生物学  信号转导  干细胞  表观遗传学  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, 
    产品应用 ICC=1:50-200 IF=1:50-200  
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 22kDa
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from Human ASCL2
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    产品介绍 background:
    Members of the myogenic determination family are basic helix-loop-helix (bHLH) proteins that can be separated into two classes, both of which work together to activate DNA transcription. Class A proteins include the ubiquitously expressed E-box binding factors, namely E2A, ITF-2 and HEB, while class B proteins, such as MyoD, myogenin and Neuro D (BETA2), are transiently expressed and exhibit a much more limited tissue distribution. Working in opposition to these positively acting factors are a specialized group of basic helix-loop-helix (bHLH) transcription factors that function as dominant negative regulators and are involved in cell lineage determination and differentiation. ASCL2 is a 193 amino acid protein that localizes to the nucleus and contains one bHLH domain. Expressed in developing placental tissue, ASCL2 binds to DNA and functions as a transcriptional regulator that is involved in the maturation of neuronal precursors in the peripheral and central nervous systems.

    Function:
    AS-C proteins are involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system.

    Subunit:
    Efficient DNA binding requires dimerization with another bHLH protein. 

    Subcellular Location:
    Nucleus.

    Tissue Specificity:
    Expressed specifically in the extravillous trophoblasts of the developing placenta.

    Similarity:
    Contains 1 basic helix-loop-helix (bHLH) domain.

    Database links:

    Entrez Gene: 430 Human

    Entrez Gene: 17173 Mouse

    Entrez Gene: 24209 Rat

    SwissProt: Q99929 Human

    SwissProt: O35885 Mouse

    SwissProt: P19360 Rat

    Unigene: 152475 Human

    Unigene: 196417 Mouse

    Unigene: 10486 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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