FITC标记的细胞增殖诱导蛋白5/肺癌相关蛋白10抗体

FITC标记的细胞增殖诱导蛋白5/肺癌相关蛋白10抗体

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  • ¥2980
  • LMAI Bio
  • LM-12337R-FITC
  • 中国/美国/欧洲
  • 2025年07月16日
  • ICC=1:50-200 IF=1:50-200
  • Human, Mouse, Rat, Chicken, Dog, Horse,
  • Human, Mouse, Rat, Chicken, Dog, Horse,
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    • 详细信息
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 靶点

      详见说明书

    • 级别

      1

    • 目录编号

      LM-12337R-FITC

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      Anti-MAEA/FITC

    • 抗体名

      Anti-MAEA/FITC

    • 标记物

      FITC标记

    • 宿主

      Human, Mouse, Rat, Chicken, Dog, Horse,

    • 适应物种

      Human, Mouse, Rat, Chicken, Dog, Horse,

    • 免疫原

      详见说明书

    • 亚型

      IGg

    • 形态

      粉末、液体、冻干粉

    • 应用范围

      ICC=1:50-200 IF=1:50-200

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      100ul

    FITC标记的细胞增殖诱导蛋白5/肺癌相关蛋白10抗体
    英文名称 Anti-MAEA/FITC
    中文名称 FITC标记的细胞增殖诱导蛋白5/肺癌相关蛋白10抗体
    别    名 1110030D19Rik; Cell proliferation inducing gene 5 protein; Cell proliferation-inducing gene 5 protein; EMP; Erythroblast macrophage protein; HLC 10; HLC-10; HLC10; Human lung cancer oncogene 10 protein; Lung cancer related protein 10; lung cancer-related protein 10; Macrophage erythroblast attacher; MAEA; MAEA_HUMAN; MGC93683; PIG5; proliferation-inducing gene 5.  
    规格价格 100ul/2980元 购买        大包装/询价
    说 明 书 100ul  
    研究领域 肿瘤  发育生物学  干细胞  细胞凋亡  细胞粘附分子  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Chicken, Dog, Horse, 
    产品应用 ICC=1:50-200 IF=1:50-200  
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 45kDa
    细胞定位 细胞膜 
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human MAEA
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    产品介绍 background:
    Emp is a 396 amino acid ubiquitously expressed adhesion protein. Expressed as 5 alternatively spliced isoforms, Emp contains one CTLH domain and one LisH domain. Emp can form a complex with F-actin, which is involved regulating actin distribution in erythroblasts and macrophages. Considered to assist with cell division and nuclear architecture, Emp is localized with condensed chromatin at prophase, nuclear spindle poles at metaphase and in the contractile ring during telophase and cytokinesis. Although the exact function of Emp is unknown, Emp is suggested to be involvement in erythroblast-macrophage cell attachment, terminal maturation and enucleation of erythroid cells, and inhibiting apoptosis of erythroblasts.

    Function:
    Plays a role in erythroblast enucleation and in the development of the mature macrophages. Mediates the attachment of erythroid cell to mature macrophages, in correlation with the presence of MAEA at cell surface of mature macrophages; This MAEA-mediated contact inhibits erythroid cells apoptosis. Participates to erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages. May contribute to nuclear architecture and cells division events.

    Subunit:
    Forms a complex with F-actin.

    Subcellular Location:
    Nucleus matrix. Cell membrane. Cytoplasm, cytoskeleton. Note=Localized as nuclear speckled-like pattern.

    Tissue Specificity:
    Ubiquitous.

    Similarity:
    Contains 1 CTLH domain.
    Contains 1 LisH domain.

    Database links:

    Entrez Gene: 10296 Human

    Entrez Gene: 59003 Mouse

    Entrez Gene: 298982 Rat

    Entrez Gene: 426024 Chicken

    Entrez Gene: 511956 Cow

    Omim: 606801 Huma

    SwissProt: Q5F398 Chicken

    SwissProt: Q3MHJ2 Cow

    SwissProt: Q7L5Y9 Human

    SwissProt: Q4VC33 Mouse

    SwissProt: Q5RKJ1 Rat

    Unigene: 139896 Human

    Unigene: 281642 Mouse

    Unigene: 101181 Rat



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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