Product overview
Description Anti-MOG rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human MOG
Reactivity Human, Mouse, Rat
Content 0.5 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol MOG
Full name myelin oligodendrocyte glycoprotein
Synonyms BTN6; BTNL11; MOGIG2; NRCLP7
Swissprot Q16653
Target Background
The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified.