Product overview
Description Anti-PLXNA2 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human PLXNA2
Reactivity Human, Mouse
Content 0.4 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol PLXNA2
Full name plexin A2
Synonyms OCT; PLXN2
Swissprot O75051
Target Background
This gene encodes a member of the plexin-A family of semaphorin co-receptors. Semaphorins are a large family of secreted or membrane-bound proteins that mediate repulsive effects on axon pathfinding during nervous system development. A subset of semaphorins are recognized by plexin-A/neuropilin transmembrane receptor complexes, triggering a cellular signal transduction cascade that leads to axon repulsion. This plexin-A family member is thought to transduce signals from semaphorin-3A and -3C.