重组人胰岛素降解酶(IDE)

特别提示：包括重组人胰岛素降解酶(IDE)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人胰岛素降解酶(IDE)
英文名称：Recombinant Human Insulin-Degrading Enzyme
产品规格：10μg|50μg|500μg|1mg

本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Met42-Leu1019在C端含有His标签。

IDE质量控制：＞95%(还原性SDS-PAGE)

IDE制剂：液体

IDE保存：收到货后请置于-20℃，可保存6个月，避免反复冻融。

关于IDE：
Insulin-Degrading Enzyme (IDE) is a secreted enzyme that belongs to the peptidase M16 family. IDE is a large zinc-binding protease and cleaves multiple short polypeptides that vary considerably in sequence. IDE plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin, and other peptides, and thereby plays a role in intercellular peptide signaling. IDE degrades amyloid formed by APP and IAPP. IDE may participate in the degradation and clearance of naturally secreted amyloid β-protein by neurons and microglia. IDE, which migrates at 110 kDa during gel electrophoresis under denaturing conditions, has since been shown to have additional substrates, including the signaling peptides glucagon, TGF α and β-endorphin.