重组人分泌型磷蛋白1(SPP1)

特别提示：包括重组人分泌型磷蛋白1(SPP1)在内，本公司的所有产品仅可用于科研实验，严禁用于临床医疗及其他非科研用途！

产品名称：重组人分泌型磷蛋白1(SPP1)
英文名称：Recombinant Human Secreted Phosphoprotein 1
产品货号：JN0615
产品规格：10μg|50μg|500μg|1mg

本品由我们的哺乳动物细胞表达系统制备而成，目的基因编码的Ile17-Asn314在C端含有His标签。

SPP1质量控制：＞95%(还原性SDS-PAGE)

SPP1制剂：冻干品

SPP1保存：
冻干蛋白置于-20℃以下可长期保存，室温条件下可稳定保存3周。
复溶蛋白溶液可在4～7℃保存2～7天，可分装后置于-20℃保存三个月。

SPP1复溶：
打开试剂管前请先离心。
复溶浓度推荐大于100 μg/ml。
冻干蛋白请溶于ddH2O。
复溶后，请根据用量分装冻存，避免反复冻融。

关于SPP1：
Secreted Phosphoprotein 1 (SPP1) is a secreted multifunctional glycoprotein. Its putative functions include roles in bone metabolism, immune regulation, wound healing, cell survival, and tumor progression. Based on gene structure and chromosomal location, SPP1 is a member of the small integrin-binding ligand N-linked glycoprotein (SIBLING) family that also includes bone sialoprotein (BSP), dentin matrix protein 1 (DMP1), dentin sialophosphoprotein (DSPP), enamelin (ENAM), and matrix extracellular phosphoglycoprotein (MEPE). SPP1 is expressed in bone, although it is also expressed in other tissues. SPP1 acts as a cytokine that is involved in enhancing production of interferon-gamma and interleukin-12 and reducing production of interleukin-10. It is essential in the pathway that leads to type I immunity. Osteopontin has been implicated as an important factor in bone remodeling. Specifically, research suggests it plays a role in anchoring osteoclasts to the mineral matrix of bones. The fact that SPP1 interacts with multiple cell surface receptors which are ubiquitously expressed makes it an active player in many physiological and pathological processes including wound healing, bone turnover, tumorigenesis, inflammation and ischemia. Therefore, manipulation of plasma Osteopontin levels may be useful in the treatment of autoimmune diseases, cancer metastasis, osteoporosis and some forms of stress.

除了重组人分泌型磷蛋白1(SPP1),，我公司还供应以下相关产品：
 

货号	名称	规格
JN0244	重组人激活素A/抑制素βA	10μg|50μg|500μg|1mg
JN0475	重组人TNFSF18	10μg|50μg|500μg|1mg
JN0476	重组人CD70(TNFSF7)	10μg|50μg|500μg|1mg
JN1902	重组人半乳糖凝集素3	10μg|50μg|500μg|1mg
JN0578	重组人胶质细胞源性神经营养因受体2(GFRA2)	10μg|50μg|500μg|1mg
JN0684	重组人组蛋白分子伴侣ASF1A	10μg|50μg|500μg|1mg
JN0885	重组人GRB2(生长因子受体结合蛋白2)	10μg|50μg|500μg|1mg
JN0919	重组人BIRC5(含杆状病毒IAP重复序列蛋白5)	10μg|50μg|500μg|1mg
JN1015	重组人MICA	10μg|50μg|500μg|1mg
JN1170	重组人UBA5	10μg|50μg|500μg|1mg
JN1179	重组人血管生成素样蛋白8(胰岛再生激素)(促代谢因子)(Betatrophin)(lipasin)	10μg|50μg|500μg|1mg
JN1220	重组人Semaphorin 4D(Sema4D)(CD100)	10μg|50μg|500μg|1mg
JN1365	重组人KLRB1(CD161)(杀伤细胞凝集素样受体B1)	10μg|50μg|500μg|1mg
JN1437	重组人ULBP-1	10μg|50μg|500μg|1mg
JN1537	重组小鼠PDGFRα(血小板衍生生长因子受体α)	10μg|50μg|500μg|1mg
JN1756	重组人Dutpase	10μg|50μg|500μg|1mg
JN1855	重组人IGSF8	10μg|50μg|500μg|1mg
ZN1619	人EG-VEGF重组蛋白	100ng
ZN1632	人FSH重组蛋白	100ng
ZN1797	小鼠Trk-B重组蛋白	100ng