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- 详细信息
- 文献和实验
- 技术资料
- 克隆性:
多克隆
- 抗体名:
Anti-STARD4 antibody
- 适应物种:
人/动物/植物
- 浓度:
1.2 mg/ml
- 保存条件:
-20°C
- 规格:
25 μl/100 μl/200 μl
Cat. No. JLC162310
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-STARD4 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Synthetic peptide of human STARD4
Reactivity Human
Content 1.2 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol STARD4
Full name StAR-related lipid transfer domain containing 4
Synonyms
Swissprot Q96DR4
Target Background
Cholesterol homeostasis s regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]).
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