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- 详细信息
- 技术资料
- 供应商:
江西江蓝纯生物试剂有限公司
- 库存:
大量
- 克隆性:
多克隆
- 保质期:
1年
- 抗体英文名:
Anti-IFT57 antibody
- 宿主:
Rabbit
- 浓度:
1.5 mg/ml
- 保存条件:
-20°C
- 规格:
25 μl/100 μl/200 μl
Anti-IFT57 antibody
Cat. No. JLC225873
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-IFT57 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human IFT57
Reactivity Human, Mouse
Content 1.5 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol IFT57
Full name intraflagellar transport 57
Synonyms HIPPI; MHS4R2; ESRRBL1
Swissprot Q9NWB7
Target Background
Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.

Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human tonsil
Recommended dilution: 50-300
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using ml225873(IFT57 Antibody) at dilution 1/85, on the right is treated with fusion protein. (Original magnification: ×200)
ELISA
Recommended dilution: 5000-10000
Cat. No. JLC225873
Package 25 μl/100 μl/200 μl
Storage -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Product overview
Description Anti-IFT57 rabbit polyclonal antibody
Applications ELISA, IHC
Immunogen Fusion protein of human IFT57
Reactivity Human, Mouse
Content 1.5 mg/ml
Host species Rabbit
Ig class Immunogen-specific rabbit IgG
Purification Antigen affinity purification
Target information
Symbol IFT57
Full name intraflagellar transport 57
Synonyms HIPPI; MHS4R2; ESRRBL1
Swissprot Q9NWB7
Target Background
Required for the formation of cilia. Plays an indirect role in sonic hedgehog signaling, cilia being required for all activity of the hedgehog pathway (By similarity). Has pro-apoptotic function via its interaction with HIP1, leading to recruit caspase-8 (CASP8) and trigger apoptosis. Has the ability to bind DNA sequence motif 5'-AAAGACATG-3' present in the promoter of caspase genes such as CASP1, CASP8 and CASP10, suggesting that it may act as a transcription regulator; however the relevance of such function remains unclear.

Applications
Immunohistochemistry
Predicted cell location: Cytoplasm
Positive control: Human tonsil
Recommended dilution: 50-300
The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using ml225873(IFT57 Antibody) at dilution 1/85, on the right is treated with fusion protein. (Original magnification: ×200)
ELISA
Recommended dilution: 5000-10000
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Anti-IFT57 antibody
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