Anti-CART/FITC抗体

Anti-CART/FITC抗体

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  • ¥2980
  • LMAI Bio
  • LM-12145R-FITC
  • 中国/美国/欧洲
  • 2025年07月10日
  • ICC=1:50-200 IF=1:50-200
  • Human, Mouse, Rat, Pig, Cow, Sheep,
  • Human, Mouse, Rat, Pig, Cow, Sheep,
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    • 详细信息
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 靶点

      详见说明书

    • 级别

      1

    • 目录编号

      LM-12145R-FITC

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      Anti-CART/FITC

    • 抗体名

      Anti-CART/FITC

    • 标记物

      FITC标记

    • 宿主

      Human, Mouse, Rat, Pig, Cow, Sheep,

    • 适应物种

      Human, Mouse, Rat, Pig, Cow, Sheep,

    • 免疫原

      详见说明书

    • 亚型

      IGg

    • 形态

      粉末、液体、冻干粉

    • 应用范围

      ICC=1:50-200 IF=1:50-200

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      100ul

    Anti-CART/FITC抗体
    英文名称 Anti-CART/FITC
    中文名称 Anti-CART/FITC抗体
    别    名 CART; CART prepropeptide; Cocaine and amphetamine regulated transcript; CART_HUMAN.  
    规格价格 100ul/2980元 购买        大包装/询价
    说 明 书 100ul  
    研究领域 肿瘤  细胞生物  神经生物学  信号转导  转录调节因子  新陈代谢  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Pig, Cow, Sheep, 
    产品应用 ICC=1:50-200 IF=1:50-200  
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 10kDa
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human CART
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    产品介绍 background:
    The CART gene encodes for a protein which has an important role in the regulation of appetite and body weight. The CART (cocaine- and amphetamine-regulated transcript) neuropeptide is an mRNA that changes in response to psychostimulant drug administration. Injection of CART peptides into the ventral tegmental area produces psychostimulant-like effects. CART localizes to areas of the central and peripheral nervous systems and is involved in feeding behavior when injected centrally. Expression of CART in the rat hypothalamus is modulated by nutritional status, and injection of synthetic CART peptide into the forebrain ventricular system suppresses food intake, indicating a possible role in hypothalamic control of energy homeostasis. Its identification in cell bodies and central terminals of vagal afferent neurons additionally suggests a role in brainstem mechanisms of meal termination and satiety.

    Function:
    CART (Cocaine and amphetamine regulated transcript protein) is implicated in reward, feeding, and stress, and it has the functional properties of an endogenous psychostimulant. It is closely associated with the actions of leptin and neuropeptide Y. It promotes neuronal development and survival in vitro.

    Subcellular Location:
    Secreted

    Tissue Specificity:
    Hypothalamus. Found in neurons of the ventrolateral part of the arcuate nucleus, in the external zone of the median eminence, and also found in terminals in the periventricular part of the paraventricular nucleus. 

    Similarity:
    Belongs to the CART family. 

    Database links:

    Entrez Gene: 9607 Human

    Entrez Gene: 27220 Mouse

    Entrez Gene: 29131 Rat

    Omim: 602606 Human

    SwissProt: Q16568 Human

    SwissProt: P56388 Mouse

    SwissProt: P49192 Rat

    Unigene: 1707 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

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