FITC标记的B细胞迁移基因2抗体

FITC标记的B细胞迁移基因2抗体

收藏
  • ¥2980
  • LMAI Bio
  • LM-0031R-FITC
  • 中国/美国/欧洲
  • 2025年07月07日
  • IF=1:50-200
  • Human, Mouse, Rat, Pig, Rabbit, Guinea Pig,
  • Human, Mouse, Rat, Pig, Rabbit, Guinea Pig,
avatar
  • 企业认证

    点击 QQ 联系

    • 详细信息
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 靶点

      详见说明书

    • 级别

      1

    • 目录编号

      LM-0031R-FITC

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      Anti-BTG2/FITC

    • 抗体名

      Anti-BTG2/FITC

    • 标记物

      FITC标记

    • 宿主

      Human, Mouse, Rat, Pig, Rabbit, Guinea Pig,

    • 适应物种

      Human, Mouse, Rat, Pig, Rabbit, Guinea Pig,

    • 免疫原

      详见说明书

    • 亚型

      IGg

    • 形态

      粉末、液体、冻干粉

    • 应用范围

      IF=1:50-200

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      100ul

    FITC标记的B细胞迁移基因2抗体
    英文名称 Anti-BTG2/FITC
    中文名称 FITC标记的B细胞迁移基因2抗体
    别    名 BTG2_HUMAN; Protein BTG2; BTG family member 2; NGF-inducible anti-proliferative protein PC3; pheochromacytoma cell-3; nerve growth factor-inducible anti-proliferative; B-cell translocation gene 2; BTG2; TIS21; PC3; TIS21.   
    规格价格 100ul/2980元 购买        大包装/询价
    说 明 书 100ul  
    研究领域 细胞生物  染色质和核信号  神经生物学  细胞凋亡  
    抗体来源 Rabbit
    克隆类型 Polyclonal
    交叉反应 Human, Mouse, Rat, Pig, Rabbit, Guinea Pig, 
    产品应用 IF=1:50-200  
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 17kDa
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 KLH conjugated synthetic peptide derived from human BTG2 C-terminus
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    产品介绍 background:
    BTG2 is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. BTG2 is involved in the regulation of the G1/S transition of the cell cycle. It modulates transcription regulation mediated by ESR1(referenced from Entrez Gene). BTG2 expression is induced in vivo during neurogenesis, and the gene is transiently expressed in vitro in rat pheochromocytoma PC12 cells after induction of neuronal differentiation by addition of nerve growth factor (NGF); suggesting that BTG2 is functionally significant during the neuronal differentiation process (PMID: 12360398). 

    Function:
    Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. Activates mRNA deadenyltion in a CNOT6 and CNOT7-dependent manner. In vitro can inhibit deadenylase activity of CNOT7 and CNOT8. Involved in cell cycle regulation. Could be involved in the growth arrest and differentiation of the neuronal precursors. Modulates transcription regulation mediated by ESR1. Involved in mitochondrial depolarization and neurite outgrowth.

    Subunit:
    Interacts with PRKCABP. Interacts with CNOT7 and CNOT8; indicative for an asscociation with the CCR4-NOT complex. Interacts with PIN1, inducing mitochondrial depolarization.

    Post-translational modifications:
    Phosphorylated at Ser-147 by MAPK1/ERK2 and MAPK3/ERK1, and at Ser-149 by MAPK14, leading to PIN1-binding and mitochondrial depolarization.

    Similarity:
    Belongs to the BTG family.

    Database links:

    Entrez Gene: 7832 Human

    Omim: 601597 Human

    SwissProt: P78543 Human

    Unigene: 519162 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

    风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。

    图标技术资料

    暂无技术资料 索取技术资料

    同类产品报价

    产品名称
    产品价格
    公司名称
    报价日期
    询价
    上海圻明生物科技有限公司
    2025年07月15日询价
    ¥2980
    上海联迈生物工程有限公司
    2025年07月15日询价
    询价
    上海莼试生物技术有限公司
    2025年07月10日询价
    ¥1100
    优利科(上海)生命科学有限公司
    2025年07月13日询价
    ¥600
    上海晅科生物科技有限公司
    2025年07月07日询价
    FITC标记的B细胞迁移基因2抗体
    ¥2980