Product overview Description Anti-ATAD1 rabbit polyclonal antibody Applications ELISA, IHC Immunogen Fusion protein of human ATAD1 Reactivity Human, Mouse, Rat Content 0.9 mg/ml Host species Rabbit Ig class Immunogen-specific rabbit IgG Purification Antigen affinity purification
Target information Symbol ATAD1 Full name ATPase family, AAA domain containing 1 Synonyms AFDC1; FNP001; THORASE Swissprot Q8NBU5
Target Background ATPase that plays a critical role in regulating the surface expression of AMPA receptors (AMPAR), thereby regulating synaptic plasticity and learning and memory. Required for NMDA-stimulated AMPAR internalization and inhibition of GRIA1 and GRIA2 recycling back to the plasma membrane; these activities are ATPase-dependent (By similarity).
Applications Immunohistochemistry Predicted cell location: Cytoplasm or Nucleus Positive control: Human liver cancer Recommended dilution: 40-200 Predicted cell location: Cytoplasm or Nucleus Positive control: Human colorectal cancer Recommended dilution: 40-200
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using ml224201(ATAD1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human colorectal cancer tissue using ml224201(ATAD1 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)