FITC标记的C-反应蛋白单克隆抗体

FITC标记的C-反应蛋白单克隆抗体

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  • ¥2980
  • LMAI Bio
  • LM-0391M-FITC
  • 中国/美国/欧洲
  • 2025年07月13日
  • IF=1:50-200
  • Human
  • Human
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    • 详细信息
    • 技术资料
    • 供应商

      上海联迈生物工程有限公司

    • 库存

      大量

    • 靶点

      详见说明书

    • 级别

      1

    • 目录编号

      LM-0391M-FITC

    • 克隆性

      多克隆

    • 抗原来源

      Rabbit

    • 保质期

      1年

    • 抗体英文名

      Anti-CRP(C11F2)/FITC

    • 抗体名

      Anti-CRP(C11F2)/FITC

    • 标记物

      FITC标记

    • 宿主

      Human

    • 适应物种

      Human

    • 免疫原

      详见说明书

    • 亚型

      IGg

    • 形态

      粉末、液体、冻干粉

    • 应用范围

      IF=1:50-200

    • 浓度

      1mg/ml

    • 保存条件

      -20 °C

    • 规格

      100ul

    FITC标记的C-反应蛋白单克隆抗体
    英文名称 Anti-CRP(C11F2)/FITC
    中文名称 FITC标记的C-反应蛋白单克隆抗体
    别    名 C-reactive protein; C Reactive Protein; C reactive protein pentraxin related; CRP; MGC88244; PTX 1; PTX1; C-reactive protein(1-205); CRP_HUMAN; Pentraxin 1.  
    规格价格 100ul/2980元 购买        大包装/询价
    说 明 书 100ul  
    研究领域 心血管  染色质和核信号  信号转导  细胞凋亡  
    抗体来源 Mouse
    克隆类型 Monoclonal
    克 隆 号 C11F2
    交叉反应 Human, 
    产品应用 IF=1:50-200  
    not yet tested in other applications.
    optimal dilutions/concentrations should be determined by the end user.
    分 子 量 25kDa
    性    状 Lyophilized or Liquid
    浓    度 1mg/ml
    免 疫 原 Recombinded CRP protein
    亚    型 IgG
    纯化方法 affinity purified by Protein A
    储 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
    保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
    产品介绍 background:
    C Reactive Protein is a major acute phase reactant synthesized primarily in the liver hepatocytes. It is a pentraxin (cyclic pentameric protein) compound of five identical nonglycosylated subunits of 206 amino acids each (m.w. 24 kDa), that are bound noncovalently to form the physiologic CRP molecule (m.w. 117.5 kDa). C Reactive Protein mediates activities associated with preimmune nonspecific host resistance. It is opsonic, an initiator of the classical complement cascade and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. Studies have revealed that among other markers of inflammation, CRP shows the strongest association with cardiovascular events. Many clinical studies demonstrated that coronary mortality among patients with unstable angina and elevated CRP is significantly higher comparing with the patients without elevated CRP. Measurements of C reactive protein (hsCRP) in the patients with ischemic heart disease provide a novel method for detecting individuals at high risk of plaque rupture. 

    Function:
    Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells.

    Subunit:
    Homopentamer. Pentaxin (or pentraxin) have a discoid arrangement of 5 non-covalently bound subunits.

    Subcellular Location:
    Secreted.

    Tissue Specificity:
    Found in plasma.

    Similarity:
    Belongs to the pentaxin family. 
    Contains 1 pentaxin domain.

    Database links:

    Entrez Gene: 1401 Human

    Omim: 123260 Human

    SwissProt: P02741 Human

    Unigene: 76452 Human



    Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

    C-反应蛋白-CRP(C-reactive protin)是与C性肺炎球菌的多糖起反应的一种蛋白,在某些细菌的感染过程中出现在血浆中。

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