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人HFE重组蛋白HLA-HHuman Hereditary

hemochromatosis protein(HFE)蛋白
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  • ¥1836
  • CUSABIO已认证
  • CN
  • CSB-EP653744HU
  • 2026年01月20日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件

      We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃.

    • 保质期

      Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

    • 英文名

      Recombinant Human Hereditary hemochromatosis protein (HFE), partial

    • 库存

      200

    • 供应商

      武汉华美生物工程有限公司

    • 规格

      20μg


    英文名称:

    Recombinant Human Hereditary hemochromatosis protein (HFE), partial

    品名简称:

    Recombinant Human HFE protein, partial

    货号:

    CSB-EP653744HU

    规格:

    20μg

    价格:

    1836

    LC-MS/Western Blot:

    /

    SDS-PAGE:

    (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

    纯度:

    Greater than 85% as determined by SDS-PAGE.

    内毒素:

    Not test

    生物活性:

    /

    基因名:

    HFE

    Uniprot No.:

    Q30201

    别名:

    HLA-H

    种属:

    Homo sapiens (Human)

    蛋白长度:

    Extracellular Domain

    来源:

    E.coli

    分子量:

    40.2 kDa

    表达区域:

    23-306aa

    氨基酸序列:

    RLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLV

    蛋白标签:

    N-terminal 10xHis-tagged and C-terminal Myc-tagged

    产品提供形式:

    Liquid or Lyophilized powder

    缓冲液:

    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.

    储存条件:

    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

    保质期:

    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

    货期:

    3-7 business days

    注意事项:

    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

    功能1:

    Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin.

    功能2:

    Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin.

    文献:

    "The haemochromatosis candidate gene HFE (HLA-H) of man and mouse is located in syntenic regions within the histone gene." Albig W., Drabent B., Burmester N., Bode C., Doenecke D. J. Cell. Biochem. 69:117-126(1998)

    研究领域:

    Metabolism

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      )的Thomas Langer,领导其科研小组研究了一类称为paraplegin(见备注)的酶。在遗传性痉挛性截瘫(hereditary spastic paraplegia,HSP)病人身上,这种酶是错误表达的。经过对酵母和小鼠细胞的实验,Langer和同事们发现paraplegin控制着线粒体当中核糖体(制造蛋白质的分子机器)组装的最后过程。 在害有HSP疾病的病人身上,失去起神经冲动作用的重要外显子,可能与线粒体错误的蛋白质合成相联系。 参考文献:The m-AAA

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    人HFE重组蛋白HLA-HHuman Hereditary hemochromatosis protein(HFE)蛋白
    ¥1836