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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃.
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名:
Recombinant Human Hereditary hemochromatosis protein (HFE), partial
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
20μg
英文名称:
Recombinant Human Hereditary hemochromatosis protein (HFE), partial品名简称:
Recombinant Human HFE protein, partial货号:
CSB-EP653744HU规格:
20μg价格:
1836LC-MS/Western Blot:
/SDS-PAGE:
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.纯度:
Greater than 85% as determined by SDS-PAGE.内毒素:
Not test生物活性:
/基因名:
HFEUniprot No.:
Q30201别名:
HLA-H种属:
Homo sapiens (Human)蛋白长度:
Extracellular Domain来源:
E.coli分子量:
40.2 kDa表达区域:
23-306aa氨基酸序列:
RLLRSHSLHYLFMGASEQDLGLSLFEALGYVDDQLFVFYDHESRRVEPRTPWVSSRISSQMWLQLSQSLKGWDHMFTVDFWTIMENHNHSKESHTLQVILGCEMQEDNSTEGYWKYGYDGQDHLEFCPDTLDWRAAEPRAWPTKLEWERHKIRARQNRAYLERDCPAQLQQLLELGRGVLDQQVPPLVKVTHHVTSSVTTLRCRALNYYPQNITMKWLKDKQPMDAKEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLV蛋白标签:
N-terminal 10xHis-tagged and C-terminal Myc-tagged产品提供形式:
Liquid or Lyophilized powder缓冲液:
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.储存条件:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.保质期:
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.货期:
3-7 business days注意事项:
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.功能1:
Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin.功能2:
Binds to transferrin receptor (TFR) and reduces its affinity for iron-loaded transferrin.文献:
"The haemochromatosis candidate gene HFE (HLA-H) of man and mouse is located in syntenic regions within the histone gene." Albig W., Drabent B., Burmester N., Bode C., Doenecke D. J. Cell. Biochem. 69:117-126(1998)研究领域:
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文献和实验Molecular Diagnosis of Hereditary Hemochromatosis
Hereditary hemochromatosis (HH) is an autosomal recessive disorder of iron metabolism with a frequency of homozygosity in the Caucasian population of 1 in 200-400. The pathophysiologic hallmark of HH is chronic, increased absorption
)的Thomas Langer,领导其科研小组研究了一类称为paraplegin(见备注)的酶。在遗传性痉挛性截瘫(hereditary spastic paraplegia,HSP)病人身上,这种酶是错误表达的。经过对酵母和小鼠细胞的实验,Langer和同事们发现paraplegin控制着线粒体当中核糖体(制造蛋白质的分子机器)组装的最后过程。 在害有HSP疾病的病人身上,失去起神经冲动作用的重要外显子,可能与线粒体错误的蛋白质合成相联系。 参考文献:The m-AAA
Reference GRIN1 138249 21 Schizophrenia 〔93〕 GRIN2A 138253 14 Schizophrenia 〔93〕 GRIN2B 138252 13 Schizophrenia 〔93〕 GRIN2C 138254 13 Schizophrenia 〔93〕 GRIN2D 602717 13 Schizophrenia 〔93〕 HBB 141900 3 ? -Thalassemia 〔94,95〕 HFE 235200 7 Hereditary
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