Anti-ITGAX antibody

Anti-ITGAX antibody

Cat. No.     JLC160573
Package    25 μl/100 μl/200 μl
Storage    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Product overview
Description                   Anti-ITGAX rabbit polyclonal antibody
Applications        ELISA, IHC 
Immunogen               Synthetic peptide of human ITGAX
Reactivity                 Human
Content                     0.3 mg/ml
Host species               Rabbit
Ig class                  Immunogen-specific rabbit IgG
Purification                 Antigen affinity purification

Target information
Symbol                 ITGAX
Full name                 integrin, alpha X (complement component 3 receptor 4 subunit)
Synonyms    CD11C, SLEB6
Swissprot    P20702

Target Background
This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles.