Product overview Description Anti-RGS22 rabbit polyclonal antibody Applications ELISA, IHC Immunogen Fusion protein of human RGS22 Reactivity Human Content 0.2 mg/ml Host species Rabbit Ig class Immunogen-specific rabbit IgG Purification Antigen affinity purification
Target information Symbol RGS22 Full name regulator of G-protein signaling 22 Synonyms CT145; PRTD-NY2 Swissprot Q8NE09
Target Background RGS22 (regulator of G-protein signaling 22), also known as FLJ75004, PRTD-NY2, FLJ40080, MGC102908 or DKFZp434I092, is a novel 1264 amino acid regulator of G-protein signaling specific to to testis. RGS22 inhibits signal transduction and contains two isoforms as a result of alternative splicing. RGS22 is found in spermatogenic cells and Leydig cells, and may be involved in the translocation of GNA13 from the cytoplasm to the nucleus during spermiogenesis. RGS22 contains two RGS domains: RGS1 and RGS2, and the gene encoding RGS22 maps to human chromosome 8q22.2.
Applications Immunohistochemistry Predicted cell location: Cytoplasm and Nucleus Positive control: Human breast cancer Recommended dilution: 25-100 Predicted cell location: Cytoplasm and Nucleus Positive control: Human lung cancer Recommended dilution: 25-100
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using ml223017(RGS22 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using ml223017(RGS22 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)