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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
Recombinant Human ER degradation-enhancing alpha-mannosidase-like protein 1 protein (46-128AA)
- 亚型:
IgG
- 形态:
Liquid
- 保存条件:
Upon receipt, store at -20℃ or -80℃. Avoid repeated freeze.
- 克隆性:
Polyclonal
- 标记物:
FITC
- 适应物种:
Human
- 保质期:
6个月
- 抗原来源:
Homo sapiens (Human)
- 目录编号:
Q92611
- 级别:
优
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 宿主:
Rabbit
- 应用范围:
/
- 浓度:
>95%,Protein G purified
- 靶点:
EDEM1
- 抗体英文名:
EDEM1 Antibody, FITC conjugated
- 抗体名:
EDEM1 antibody;EDEM antibody;KIAA0212ER degradation-enhancing alpha-mannosidase-like protein 1 antibody
- 规格:
100μl/50μl
| 规格: | 100μl | 产品价格: | ¥1320.0 |
|---|---|---|---|
| 规格: | 50μl | 产品价格: | ¥880.0 |
保存缓冲液
Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
功能
Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It has low mannosidase activity, catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2.风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验Protein Degradation Via the Proteosome
It is becoming apparent that an increase in the rate of protein degradation represents one mechanism for the regulation of key proteins during the cell cycle (1 ). The importance of protein degradation in the control of cell proliferation
The Measurement of Protein Degradation in Response to Oxidative Stress
Molecular oxygen is an excellent acceptor of electrons and is therefore employed by nature for a wide variety of highly important biochemical reactions. The chemical reactivity of oxygen, however, also leads to the formation of oxygen
Regulation of Krpple-Like Factor 5 by Targeted Protein Degradation
Transcription factors are usually unstable proteins. The degradation of the majority of transcription factors is through the ubiquitin proteasome pathway and is tightly regulated by E3 ubiquitin ligases. KLF5 is an important transcription
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